FULVIC ACID EXTRACT PRODUCT FOR TREATMENT OF FINE LINES AND WRINKLES IN FACIAL SKIN
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Discover the most powerful anti- aging and rejuvenating elixir ever known to mankind. Feel  the  amazing power of growing young. 


"A worst doctor cures the disease. An average doctor cures the disease and prevents it's recurrence. But the best doctor prevents the disease from occurring"
.. fulvic acid extrac for
wrinkles in facial skin
fulvic acid is a family 
of organic acids
fulvic acid is a naturally occurring organic product
fulvic acids are natural compounds
isolation-of-fulvic acids from aqueous solution
miracle minerals fulvic acid

multi vitamin and mineral supplement
native shilajit
shilajit based fulvic acid
 
fulvic acid molecules
 
 
the fulvic acid
 
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SHILAJIT -FULVIC ACID Rejuvenation elixir. Purest Himalayan SHILAJIT
 
 
 
 


 

SHILAJIT -FULVIC ACID Rejuvenation elixir. Purest Himalayan SHILAJIT
 
 
 

This invention relates to a composition of acylated oligopeptide and aqueous fulvic acid extract product for treatment of fine lines and wrinkles in facial skin by improving fibroblast matrix and a method of using the composition. Preferably, the acyl oligopeptide is a palmitoyl hexapeptide based on the amino acids phenylalanine, alanine, leucine and lysine. The fulvic acid is the water-soluble fraction of acidified humus, obtained from naturally occurring peat. The composition may contain dimethylisosorbide or ethoxydiglycol as solubilizing and penetration enhancers for the acyl-modified oligopeptide and other preferred skin beneficial ingredients.
BACKGROUND OF THE INVENTION

U.S. Pat. No. 6,875,744 B2 specifies short bioactive peptides that are primarily made from phenylalanine, alanine, leucine and lysine. Such peptides are water soluble or miscible and have been reported to offer a low in-vitro minimum inhibitory concentration (MIC) against P. acnes . Benefits for hydrophobic acylated peptides of similar sequences have been reported include increasing cell density of fibroblast cells in the Cyquant cell proliferation assay (Molecular probes, C-7026) due to boosting the immune system by acting like a host defense peptide. Host defense peptides boost the innate immune system and have been shown to have a number of immunomodulatory functions including altering host gene expression, acting as chemokines and/or inducing chemokine production, inhibiting lipopolysaccharide induced pro-inflammatory cytokine production, promoting wound healing, and modulating the responses of dendritic cells and cells of the adaptive immune response. The boosting of such aspects of healthy skin are the same as are required for younger and less-wrinkled skin.

It is not generally recommended that such peptides be stored in solution. However, the shelf life of peptides is extended for sequences not containing Cysteine, Methionine, Tryptophan, Asparagine and Glutamine.

Peptides are not very useful if they are insoluble in the aqueous buffers required for testing in bioassay systems. Peptides can be made more lipophilic with C2-C22 alkyl esters or amides on the terminus to modify the interaction of the peptide with skin lipids but this modification drastically changes the solubility and makes peptides even more difficult to deliver in a stable aqueous cosmetic vehicle. Many biochemists use dimethylformamide or dimethylsulfoxide to help dissolve peptides for aqueous bioassay. Both of these solvents are not considered acceptable for cosmetic use. Solvents like ethoxydiglycol or dimethylisosorbide are useful cosmetic solvents for enhancing skin activity and can help solubilize the lipophilic peptide in an oil phase. Formulation of excess lipophilic solvent can remove surface lipids and leave the skin feeling dry or brittle. U.S. Pat. No. 4,814,173 teaches the combination of dimethylisosorbide, peptide and silicone elastomers as part of a preferred transdermal matrix system.

Fulvic acid is the water-soluble fraction of acidified humus. Humus is the naturally occurring decomposition product of vegetation as found in peat sources. Fulvic acid is thought to aid transport of minerals to cells. US application 20060257437 (Ingman) used a combination of water, silica, and optionally silver ions, in a cosmetic containing fulvic acid for concealing wrinkles and improving skin condition, but did not employ peptides in the cosmetic specification.

Commonly assigned application Ser. No. 11/654,406 was filed on 17 Jan. 2007, claims the benefit of the 18 Jan. 2006 filing date of Provisional Application Ser. No. 60/760,034, and is incorporated-by-reference in its entirety. Ser. No. 11/654,406 discloses that specific short chain acylated peptides in combination with lycium barbarum (goji berry) glyco-conjugates lead to improved dermal fibroblast activity, resulting in anti-wrinkle benefits in cosmetic applications. 
 

 



What Is Special About of our Shilajit?
 

  • Our manufacturing facility is ISO 9002 Accredited and we are registered with United States Food & Drug Authority (USFDA)
  • We use a patented process including freeze drying, vacuum filtration and reverse osmosis process to achieve highest concentration of Fulvic Acid and ionic minerals. 
  • Each capsule of our shilajit contains "1000 mg of Shilajit extract". Most of other's offer only "500 mg Shilajit"
  • We offer you lowest price guarantee
  • Our Shilajit does not contain any heavy metals.
  • We are not interested in merely selling shilajit. We want you to genuinely benefit from our shilajit and recommend it to others.

Order- 4 Months supply 

Each packet contains 30 capsules of 1000 mg Shilajit

Total of 4 Packets - 12 Strips containing  120 capsules - 4 Months course - Taken 1 capsule a day. Each capsule contains 60% Fulvic Acid. 
 
U.S.$ 49

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Note: The therapeutic effects of  SHILAJIT has not been evaluated by US FDA.  SHILAJIT is not intended to diagnose/treat or cure  any ailment. Individual results may vary.
 

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